For more information, visit our course guide
This workshop provides an introduction to the NCBI molecular databases and how to access the data using the Entrez text-based search system and BLAST sequence similarity search tool. You will learn the varied types of available molecular data, and how to find and display sequence, variation, genome information using organism sources (Taxonomy), data sources (Bioproject) and emphasizing the central role of the gene as an organizing concept to navigate across the integrated databases (Gene, Nucleotide, Protein, dbSNP and other resources).
Participants will attend this workshop via webinar hosted in the HSL 307 classroom.
(Basic Bioinformatics Tools Series)
In this workshop, you will find, display and analyze microarray and sequence-based expression data that are stored in the Gene Expression Omnibus (GEO), Sequence Read Archive (SRA), UniGene, and Epigenomics databases to investigate the potential for expression of transcript splice variants and examine the levels of expression under varied experimental conditions as well as in different tissues and disease states. You will analyze Microarray data the on-demand GEO2R tool and will explore the precomputed transcript analyses that are displayed on the UniGene and GEO Profiles pages. You will explore genome-aligned RNA-Seq data through the Gene database's sequence viewer displays and analyze raw RNA-Seq reads in the SRA database using NCBI's SRA-BLAST service.
In this workshop, you will learn to use and access resources associated with human sequence variations and phenotypes associated with specific human genes and phenotypes. The workshop will emphasize the Gene, MedGen and ClinVar resources to search by gene, phenotype and and variant respectively. You will learn how to map variation from dbSNP and dbVAR onto genes, transcripts, proteins, and genomic regions and how to find genetic tests in GTR. You will also gain experience using additional tools and viewers including PheGenI, a browser for genotype associations and the new Variation Viewer the 1000 Genomes Browser, which provide a useful ways to search for, map and browse variants as well as upload and download data in genomic context.
In this workshop, you will learn how NCBI processes genome-level data and produces annotation through the prokaryotic and eukaryotic genome annotation pipelines. You will find, browse, and download genome-level data for your organism of interest and for environmental and organismal metagenomes using the Genome, BioProject and Assembly resources. In addition to assembled and annotated data, you will retrieve and download draft whole genome shotgun and read-level next-gen sequencing data from the Nucleotide and Sequence Read Archive (SRA) databases. You will access results of precomputed analyses of genomes, as well as perform your own analyses of assembled and unassembled genomic data using NCBI's genome BLAST and SRA-BLAST services.
Allied Health (UNC-CH)
Public Health (UNC-CH)
UNC Hospitals / Health Care System
HSL staff (UNC-CH)
Other Health Affairs at UNC-CH
General public and other affiliations (incl. other institutions, corporations, etc.)
(incl. visiting scholars)
Faculty Based Off Campus
Staff Based Off Campus
Distance Education Student
Fellows & Post Docs
Residents / Housestaff
You will receive an email confirming your registration. If you have questions about classes,
or haven't received a confirmation, please email Education Services at:
firstname.lastname@example.org or call us at (919)962-0800.