This question is too vague. We don't know what the test is used for or what it is being compared with to determine its accuracy."); write(""); } fenster.document.close(); } function q2() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
We're getting close. But we still don't know what gold standard test will be used to determine the accuracy of the FlexSure test."); write(""); } fenster.document.close(); } function q3() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
This is a good clinical question. We know the patient problem (suspected H. pylori), the intervention (near patient, FlexSure test), the comparison (ELISA test) and the expected outcome (accuracy for positive diagnosis)."); write(""); } fenster.document.close(); } function q4() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
This strategy can work. However very often you will not find enough information by just searching on the brand name.
If you don't find enough information, you will need to formulate a strategy that gets at the concepts rather than the brand name."); write(""); } fenster.document.close(); } function q5() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
We are concerned with the reliability of the test to detect H. pyloria. This search strategy includes part of the patient problem (suspected H. pyloria), the intervention (blood test or FlexSure or near patient test), the comparison (ELISA) and the outcome (sensitivity and specificity)."); write(""); } fenster.document.close(); } function q6() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
While our patient has dyspepsia, using it in our search strategy may be too limiting. This strategy does not address the outcome (accuracy) which is crucial to the question. "); write(""); } fenster.document.close(); } function q7() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
A 7ml blood sample was taken from each patient. The FlexSure test was administered at the various sites. Then the remaining blood was sent to University Hospital were all samples were also tested with the ELISA assay by a single operator blinded to the FlexSure results. (under Methods, p. 1237.)"); write(""); } fenster.document.close(); } function q8() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
see the discussion under Methods, p. 1237."); write(""); } fenster.document.close(); } function q9() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
Patients were from an appropriate spectrum representing a wide range of ages, duration and severity of symptoms. Patients were recruited from 43 general practices in England."); write(""); } fenster.document.close(); } function q10() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
See the discussion under Methods on p.1236-7."); write(""); } fenster.document.close(); } function q11() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
389 of the 394 patients were tested by the reference standard ELISA assay regardless of the results of the FlexSure test. 5 patients did not have serum available for the ELISA testing. (See Results p. 1237)"); write(""); } fenster.document.close(); } function q12() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
See discussion under Results on p. 1237."); write(""); } fenster.document.close(); } function q13() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
The testing is adequately described on p. 1237. Note that the FlexSure test was performed by a number of different clinicians, some with centrifuges, some without. The ELISA test was conducted by a single operator. Both product manufacturers are listed."); write(""); } fenster.document.close(); } function q14() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
See discussion under Methods, p.1237-8."); write(""); } fenster.document.close(); } function q15() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
This is a well designed study according to ACP Journal Club."); write(""); } fenster.document.close(); } function q16() { fenster = open("", "Anzeige", "width=200,height=300"); fenster.document.open(); with (fenster.document) { i++; write("
There are no major problems with the study methodology."); write(""); } fenster.document.close(); } function close() { fenster.document.close(); }